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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50be9cf23bf48d80b204e94a7f7e8d80994c5f0f4ebb0a5cb1554b8ad3aadfea' 
  AND token = 'a5apUAephxT1MkmDvH8VM6j5AnD3Z43ZdW8LCDXk5Jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}