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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '324ca78b19ee04c94768b81c620351dd2239f2584ddf4288e7ed36582eb1efb3' 
  AND token = '9VJz7d5XK8FrJCXvtdzK+DRiyeXNYjuJ2lXRyMirntA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}