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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a1489afc1f65e33d36ecb871fd9beadea95f4fadae26b37ab03fc5edcba8710' 
  AND token = 'kHNjLkh/lJxHnrqb7K5VO6awOWeFcLM0KcfVVUWjOHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}