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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '748e7759943c5fc313e8c3881557c73b9e080af33fa829d9ee8aee3854b254b4' 
  AND token = 'GwoLmfe+I0KS09pRr352DR7Sr33jCZm5cJ4wt4XhvRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}