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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5705a0b4afabd7e64629bfd77872aed2115ec4191dbf484fb7aadb326faf3e2e' 
  AND token = '8wvr9cr43krrnvIQkWLqA1MZm8QDdOABH31+uAxWOac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}