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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '900ab773b3dd14f19f09ee0755a9a332fb7b850ee43c17ee67d269a92a15e7f3' 
  AND token = 'XTi/TttG++Z1DQTHa6C0OFtKY32rqnMHzGVfMCgJRCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}