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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '953e8b32a066bd777bc315e8545e1f5fca5bd02ebc002a4d97255afd7eb39164' 
  AND token = '5i0esJc0Gw6UmpICCP66kMA9DtrFga5rPdBNNM2yNEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}