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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c05e9d8ee1d72557463248cea4d4acc71e72bde54456c6c44868367a2ae22bd5' 
  AND token = '+vm+wc2ani2sYOibmvr1UoB7b1/KH7b3LEeSVzNucHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}