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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67f9f63d725c7b21f229c96ea4e179512ac8400691e6724535bfd8887b1fe877' 
  AND token = 'V+sBH38AV3hMsbfmAEqwcMzIO5i+jMCsibdF2E44UMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}