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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ace2d444bd799e89f727fe950574089b3d933fc0f26db7d9e18fb894afc23624' 
  AND token = 'Uq55d+ALaM/vp46L8dNJu/NCxQ/O02cBjP7SyxFP67E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}