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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '739debe68bf52f82b01ae33996ba0b4d0611e8964d8a6017ebb9686e6e80d332' 
  AND token = 'QWpAC709p/lRyd7eLylRzNBS3luaBrkLTlBXyBQSBtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}