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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26f0439c60b6d84bff0c08f94156b94ee6fd335ac9b843a74c3ece311b3bd310' 
  AND token = 'MfEOZI6eXXV8PgaQQ5xTlVMMCdi3mEPC0agDwZ7BB/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}