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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed68620a7a495196072f30308d62977d0191d9be0df8200ca625134d20f9de9b' 
  AND token = 'oMFuZA5q+9UGt2NH4G3CfGBTXVoSjhR+0yMm3NVAxT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}