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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88d35fffea47d55496e0f7ea73c45302ac224fd6219920943476698d36fa2209' 
  AND token = 'Ddv28nug5gdza+XRW3O+rDjehcnvR2/h3P+1pii6i9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}