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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a1d0e22d6522fa87f2623f206e76301e362f347253edd9e84220a299656c07a' 
  AND token = 'NVIku5W5do4C8bPhvc1W1CibK7hWnrdzD/lwZWuPNAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}