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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcdbbcdb33ab3cfcda79c60e24e2512a12451b478f7baff1672610690483ef0e' 
  AND token = 'zSo3GfaMbdDnmCn+u8UDgQ5Af50n2j3WXdVmhJQifI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}