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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0ec7be51a10c536b05837135b6f4ae8ae5323f2c492d27e7d61b3169746f838' 
  AND token = '5tcZPeM11SwfPk2ETmY/sdmqgaJ1eDsU8ImWVU3jyUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}