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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07f6d5fc51eb27be3a682c571c18e5cc9d7ff5af235393a279234b517f34ce75' 
  AND token = 'PxB5aV58RQSGHZ7DIx8cX9sCGi4ybnF46D5NHE5VvK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}