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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e64806e5521294b2cb34cc3c5ae0f4c343297bc45c3bf1f680388af350d5c23' 
  AND token = '2LmroHf3+VHVmNTUQamThBtlxI7e2hJgr4r3e7OmYos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}