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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5130accae9c59a54f8ef464bfde4e14fd4e8f3f2aa6b59784a1c3121b3006935' 
  AND token = 'yE3MYOATwocuVWrksAxIWKzg24l0nXh3dUulIvjpfy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}