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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eec974aa29a890f6b955fbb2d0ce7d5bdf572a80985b34d5a339c53446b7216' 
  AND token = 'E0aXlTuxs1WQPbWdBqM7epUzNhSjglVGCOnV2/5bop4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}