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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74763125263c945a93aa5675fc24e52a90e7c111157bc15ba623094275b2fefb' 
  AND token = 'DEKiG2T/SVgT9I/79+AP+hEvT/fmfbVrvB9fY1OIrTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}