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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67d885c2f657d15b3cd6a9a0cc82795b0dd2d4f7d9517c02c591f8e5dc94d754' 
  AND token = 'HmtPygbD7YaAFR88sAZ879aDMrIKnrk32zltFsuS+AI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}