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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8206ea44a36d9cac5df1040cc1fc1d684f0a9ee77538506c4856c39d98c38c58' 
  AND token = 'OtMj8mTS6MVlET+PD/HY88d7icoHSuJPqF6Sg67cjGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}