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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '885ce078b9ae9270dd14cc432af8fef4f4401ea46894ba2e60457af7ed4561ba' 
  AND token = 'RGYKbZnhtv5ZouiAvUkOIpdAJMd2bHUIkptW6RT1JIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}