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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '792f249d3a9b7dba9a2d3fb02382df924483bdb8d9c42d56b63504d3191b0f85' 
  AND token = '28/akI5CfMofrp+03awOWZHsfmSE04ATAzFbHhOJbhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}