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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d95ed276bd3245e4dcc608cb2e89fd018d5bf7896eb0ce2f4114f105c5bb1fd' 
  AND token = '6z5t3Af+5I7xARfvFBa+qAqNxoO48ER82kSYgq7Dg3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}