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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f77e320571e9642917b7e6366f965acd56401e4b7d3c1addd1f62a4bce4d9c83' 
  AND token = 'LmoyrV+QHQKRDf6ncG5nIU8exH6uHcrMRS1BFCbh6DU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}