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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc25143ed6ce8b70f584ce9d9d18e247106b4e9356243f0e3f267f33f7d8fcc2' 
  AND token = 'z+NzLA22hIXDXVC22w3UOjK22ff4QHDJ2Aq/TNLqKB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}