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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd88c4a37a83bf39862aa779b6a98ada522207f3b457f4ae04d834de5f312090a' 
  AND token = 'ezfpf3cMjrVon29Z1oyCwemXv+hsEz01ODms20menpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}