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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52bea6a4109e8c9c013746d3c11cec025b4cd6e9b96e6147a42e6bc34a6b0d34' 
  AND token = 'dQmKm3EQHQZSCYgGaRKRp31xSXB7vNIVe27LhrBr2Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}