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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a61a46790dbeaf79d6635902fc08a07851bdf2d8f1e04959fc9d117018ed603d' 
  AND token = 'M+onpIptOvByEK4MJKYjvjs+e6880jSW4bLkub20qSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}