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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b6ee787aef4a5a20f7c764e63778dbc0fbb7d62809e524568b83c9d49b47e41' 
  AND token = '0EvGfMvZA0oaFNwn8Qzd7KnZsKTZ47VKivy8a0tqLEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}