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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed9069765bd5b0e1e7a4feb59124bc4fef4b4a6ed4c52aa848cb5f7ed4b15d61' 
  AND token = 'wPcpUDn6ikGRFZObkPTSFxD5SZdUneGKteNmDCjrbj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}