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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3277359d84f0aa1931d0ec7da359418ecaf72ccc440fae8f76247e7f6c3cf7d' 
  AND token = 'B9eYUPQtHORB/Ty3xo014c7xfQX9hwrxA4xtQwW0pOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}