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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2cfdc65c16cd82908163c0d3fa3bbafb13135e916c077cd764c26dda83282f9' 
  AND token = 'aanvFYNFsDB5xePFd5N26bnS0jGhkqrOVpE0Q0eM5+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}