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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e321ed1a763a16a3613e3e72df0f88eb566902e3f0a7c6718ef149aca7c98eaa' 
  AND token = 'XiMEonVsJNbwhC8n3FPEmjPaInxUK+3WI1IjpxPyHFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}