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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87c8c1a3709ed62833b553949b3e507ee2099e3319a72d2c6e94645f5b3f5fa0' 
  AND token = 'ExszMZTN1vdMsuEWzhhub64JvUOdoDw0FBqDHULVENU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}