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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9df2cb084c86b09f3f678f1429fc29d5750ab110662fc121e97e5ff3024c9595' 
  AND token = '4lEx2U6K2W9o5uGrs+1uj84rSRjUaq3Bo5FPPI/W8k8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}