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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2dfd566e751b672ad3a30eaea815a148551cfc6d32d727355c6d130f8445d49' 
  AND token = '3LfDb4ktToDranpoCUobK5o28hh41+OsRzQMNS0DdBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}