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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eb7d43a7427b221e67234227f3c52a7442721f57171e934d508b0b7fae1806c' 
  AND token = 'xrF5Hmd7RCVmaenmgZtrdENhdvpDMmsHVpjLuuAdcY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}