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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a3a804d92c0387dc556b1bc99b4e5daa534d888f59411958e9188b4c51fe0d2' 
  AND token = 'WVeFguBWdQvr6QidBE7W2JOQt/slMbRuqZFRdnIhd5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}