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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '927c3c2b243618a52fcd8dab7be4810f147c07e2a57e022c2170168be44aa730' 
  AND token = 'WxKYQDGJR/8qvf/nADGenafKOREXeWRcg1Ro/qMRVMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}