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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291cd9232b6e718b5839440b7a7928dcea5da37f811fdcbca9bf270489277b60' 
  AND token = 'lc+s/QZ6dedZxPk5eotSBBEEIF71fWepIkGv6KrT6zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}