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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '868e24b8de4d624128f3679a032ada60dba7b157e058e62e9bba75a687b66bbf' 
  AND token = 'skmzp135+x3SPZt3v5oQ6w6UoqLCdrMtb3AddakCHg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}