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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8627d6cbf3de7976d9f97238e4b8e6973fa6363778ef7e44021ec8f3b239851' 
  AND token = 'ADW9jn6EvhpbS+rGY25RsYfUGkRKrNmPfsgrid6AEvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}