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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '333bd018b76c127c9ad4ecd21dc29013c11ba9ee38cf7b9801e9b6017d4e4240' 
  AND token = 'B63t1xdqyEuDSxvH5SiFY+Yjp7xyokm1RO2s0UEtnTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}