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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f8f6cb0619eb30d8658d2b903135b36d2e1794ff863b7fffc61a9c7a4aeac3' 
  AND token = 'OyR6h+g31Lut5yzEDgP4N+BjtEHOoNXkbAP2ADl9LBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}