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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3aa5ba99c60eb345df96dc0c092316832c8c0dc2e5627cab5d49c2cd67278c' 
  AND token = 'qTS5tB4FKstYIngxwG5WmoRr01TtOuv/ypUJExXktnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}