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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef01017d76f98325e5d69a0e51dcdbf213b446dd21a0dd4088ec3bbd970f97da' 
  AND token = 'c+ImL58/vTylfPwW/5e82Lof4DstzE3hN6RtQN4x5tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}